1Associate Professor, Department of Oral Pathology, Faculty of Dental Sciences, SRIHER
2Professor & Head, Department of Oral Pathology, Faculty of Dental Sciences, SRIHER
3Principal/Professor and Head, Department of Pharmacognosy, Faculty of Pharmacy, SRIHER, Porur, Chennai
4Chief Scientist and Head (Retd.,), Department of Biotechnology, CLRI, Chennai
*Corresponding Author: Dr. Sharada. T. Rajan, Mds., Associate Professor, Department of Oral Pathology, Faculty of Dental Sciences, Sriher, Porur, Chennai, 600 116. Phone: + 91 98400 82472, Email: dr.sharadaganesh@yahoo.co.in
Online published on 11 July, 2019.
To assess the antibacterial and antifungal activity of Psidium guajava leaf extract.
Two concentration of alcohol extracts were obtained by Soxhlet method and another extract was prepared with aqueous extraction method. All three extracts were assessed for antibacterial and antifungal activity using well-diffusion method.
70% ethanolic extract (S3) showed more antibacterial efficacy when compared with 100% ethanolic (S1) and aqueous extracts (S2) of Psidium guajava. Antifungal activity screening showed inhibitory zone of 13 mm with S1, 14 mm with S3. Aqueous extract (S2) could not show any effect on Aspergillus niger growth inhibition. Candida albicans inhibition was comparable among the three extracts. Higher concentration 1024 ug/ml of S3 showed superior efficacy of 17 mm when compared to other two extracts S1 and S2.
The findings of this study revealed the antibacterial and antifungal properties of the Psidium guajava leaf extract.
Antibacterial activity, Antifungal activity, Quercetin, Psidium guajava, Polyphenolic flavonoids
