Indian Journal of Public Health Research & Development

  • Year: 2019
  • Volume: 10
  • Issue: 6

Effects of Birth Weight on Cord Blood Thyroid Stimulating Hormone

  • Author:
  • Krishnaji L. Garud1, Ajit V. Sontakke2, Anuja A. Pawar3,, Dhirajkumar Mane4
  • Total Page Count: 4
  • Page Number: 321 to 324

1Assistant Professor, Department of Biochemistry, Krishna Institute of Medical Sciences, Karad, Maharashta (India)

2Professor and HOD, Department of Biochemistry, Krishna Institute of Medical Sciences, Karad, Maharashta (India)

3Tutor, Department of Biochemistry, Krishna Institute of Medical Sciences, Karad, Maharashta (India)

4Statistician, Directorate of Research, Krishna Institute of Medical Sciences “Deemed To Be University”, Karad, Maharashta (India)

Abstract

There is a possibility of an association between birth weight and Cord blood Thyroid Stimulating Hormone (CbTSH) level. Congenital hypothyroidism (CH) is most common preventable cause of mental retardation in neonates. CbTSH level is a well known screening tool for CH.

Cross sectional study was designed. A total of 462 neonates were studied for TSH levels by Chemi-Luminescence Immuno Assay (CLIA) technique.

Comparison among birth weight outcome was done by using unpaired t-test. Pearson correlation was calculated to find out significance within groups of birth weight.

In this study the mean birth weight (grams) of the neonates was 2810.62 S.D). 365 neonates had birth weight more than 2500 g and 97 neonates had low birth weight of less than 2500g. There was no significance between birth weight and CBTSH.

Birth weight does not affect TSH values of term neonates.

Keywords

Cord blood thyroid stimulating hormone, congenital hypothyroidism, newborn screening