1Department of Medical laboratory technology faculty of Apply Medical Sciences, University of Tabuk, Saudi Arabia
2Alamal Hospital, Bahri-Sudan
*Corresponding Author: Dr Aadil Yousif Assistant Professor, Department of Medical laboratory technology Faculty of Apply Medical Sciences, Tabuk University, Saudi Arabia Email: aadilyousif@yahoo.com
Online published on 11 July, 2019.
The present study aims to investigate the changes in platelets count, Mean platelet volume (MPV) and Platelet Distribution Width (PDW) in preterm and full term proven diagnosed as septic neonates and their correlations with birth weight and gestational age.
After taking approval from ethical committee of Ministry of Health (Sudan). The attending nurse collected peripheral blood samples under aseptic precautions in EDTA blood container at bedside in the period from June 2016 to March 2017. A complete hemogram was performed using AbX Micros ES60 haematology analyser.
200 cases included in this study, 113(56.5%) males and 87 (43.5%) females. Full term babies’ account for78 (39%) while premature babies account for 122 (61%). Thrombocytopenia was present in 115 (57.5%) cases, in which 83 (72.2%) had mild and moderate thrombocytopenia, and just 32(27.8%) had developed severe. 76 (66.1%) of the cases of thrombocytopenia are premature babies and 39 (33.9%) are full term babies. There was significant difference in platelets count between full term and preterm p value 0.008. In platelet indices, MPV and PDW were significantly increased in all cases, but there was insignificant difference in platelets indices between the preterm and full term babies p value 0.125 and 0.958 respectively.
Variation in the degree of thrombocytopenia and platelet indices was seen in neonatal sepsis. Severe degree of thrombocytopenia associated with proven sepsis. MPV and PDW was significantly increased in in all cases with sepsis.
Sepsis, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), Platelets Count
