1MBChB, FIBMS Neurology, Department of Medicine, College of Medicine, University of Kirkuk, Republic of Iraq
2MBChB, CABOG, FICOG, Head of Gynecology and Obstetrics Department, College of Medicine, University of Kirkuk, Republic of Iraq
Online published on 11 July, 2019.
Migraine is common neurovascular disorder in Iraq. Hormonal effect in migraine headache and severity is proved by many authors although the mechanism of hormonal effect in pathogenesis of migraine in women is still unknown.
To find out the role of hormonal changes in development of different types of migraine among women.
The design of current study was cross sectional which carried out in outpatient clinics of Neurology and Obstetrics & Gynecology departments of Teaching Hospital in Kirkuk city for duration of 1st of January to 31st of December, 2018 on sample of 100 women with migraine. Fourteen women were diagnosed as migraine with aura (MA) and 86 women were diagnosed as migraine without aura (MWA). The estradiol, progesterone, leutinizing, follicular stimulating and prolactin hormones were assessed and according to menstrual phases.
The progesterone hormone mean in both phases (follicular and luteal) was significantly higher among female patients of MWA. The estradiol hormone level at luteal phase was significantly higher among female patients having MWA. The estradiol hormone level at follicular phase was significantly higher among female patients with mild MWA. The mean prolactin hormone was significantly increased with increase in severity of MA and MWA.
The changes in reproductive hormones had a prominent role in development and severity of migraine in women, mostly migraine without aura.
Hormonal role, Migraine with aura, Migraine without aura
