College of Medicine, Department of Physiology, University of Kirkuk, Kirkuk, Iraq
Online published on 11 July, 2019.
Osteoporosis is a growing public concern of elderly persons. It is a disease characterized by low bone mineral density (bMD) which is a direct consequence of fractures. Therefore, Osteoporotic is the primary cause of disability. However, despite being studied intensively throughout the past decades, there still many concerns about its etiology that need to be investigated.
100 female patients aged 40–80 years old are enrolled in this work. Separately, all these patients are those who referred to rheumatology units/Azadi teaching hospital in the Kirkuk city for eighteen months (from February 2015 to July 2016). Half of them had osteoporosis confirmed by Dual Energy Xray Absorptiometry (DEXA-Scan), whereas the remaining patients were controls. We measured the mineral vitamin D, calcium (Ca), phosphorus and alkaline phosphatase in the sera of the entire participant.
One hundred women participated in this work with the mean age of (61.0 ± 10.2) years were studied. 50% of them were in the control group, and 50% of them had osteoporosis. Age of osteoporosis group (61± 10.2) was significantly higher than control groups (56 ± 9.0) years. Additionally, Body Mass Index significantly higher (p < 0.001) in osteoporosis (29.1 ± 5.9) compared to the control group (28.9 ± 3.4).
We conclude that there is no greater association among serum Calcium, Phosphors and alkaline phosphates with bMD. Additionally, the results showed a positive association between vitamin 25 (OH) D levels and age.
Osteoporosis, Vitamin 25 (OH) D, Calcium, Phosphorus, Alkaline Phosphatase
