1College of Medicine, Department of Chemistry and Biochemistry, Al-Mustansiryia University
2Assist. Prof., College of Medicine, Department of Chemistry and Biochemistry, Al-Mustansiryia University
3Prof., Obs and Gyn Department, College of Medicine, Department of Chemistry and Biochemistry, Al-Mustansiryia University
*Corresponding Author: Olaa Riad Kadim, College of Medicine, Department of Chemistry and Biochemistry, Al-Mustansiryia University, Baghdad, Iraq, Email: lolaa_lolaa@yahoo.com
Online published on 11 July, 2019.
Recurrent pregnancy loss is define as the spontaneous loss of three or more successive pregnancies before 24 weeks of gestation. Heavy metal may play a role in recurrent pregnancy loss. Case control study included 90 women, thirty of them were patients diagnosed with recurrent pregnancy loss between (7–20) weeks of gestation and the other sixty controls were (30 ongoing pregnant women and 30 non-pregnant). Serum levels of Chromium (VI) and Manganese was measured by using graphite furnace atomic absorption spectrometer technique. While total serum iron was measured by colorimetric method. The result were expressed as mean ± standerd error of mean. P value of < 0.01 was considered to be statistically significant. The levels of serum chromium and manganese were significantly higher in patients with recurrent pregnancy loss compared to control groups, while the concentration of total serum iron was significantly lower in patients with recurrent pregnancy loss compared to control group. As conclusion, it can be concluded that high levels of chromium (VI), manganese and low level of iron increase the risk of spontaneous pregnancy loss in Iraqi women.
Recurrent pregnancy loss, Chromium, Manganese, Iron, Graphite Furnace Atomic Absorption Spectrophotometry
