Mustansiriyah University, College of Science, Biology Department, Baghdad. Iraq
Female reproductive is deteriorating during CKD by a disruption in (hypothalamic-pituitary-gonadal axis). Our interest was to study the Anti-Mullerian Hormone (AMH) in CKD patients, with the possibility that CKD (not kidney failure) may effect on women AMH levels in CKD and/or PCOS, and the affection possibility of PCOS on kidney function. Eighty female involvement in this research (26–40) years old divided in to: twenty female as a healthy control. Twenty female PCOS group. 3) Twenty CKD group. Twenty female patients suffering from both CKD and PCOS (CKD+PCOS). This study conducted between (April 2015 to August 2017), in Baghdad. AMH was sub normal in CKD patients with a significantly higher level of LH (P ≤ 0.01), Uric acid, urea, Creatinine, monocytes and AMH was elevated in PCOS patients, uric acid correlate positively with and monocytes and negatively with AMH, also uric acid, LH, AMH and monocytes were significantly high (P≤0.01) in CKD+PCOS group. Uric acid negatively affect AMH levels in women, AMH is not a good diagnostic indicator of PCOS status, if blood uric acid was high. PCOS may cause hyperuricemia leading to kidney failure. Kidney function showed be tested rottenly in any suspected case of PCOS.
Anti-mullerian hormone, Luteinizing hormone, Polycystic Ovary Syndrome, Chronic Kidney Disease, uric acid, monocytes
