1B.D. S, M. Sc, Department, Dentistry College, Mustansiriyah University, Baghdad, Iraq
2M.SC, Ph. D., Dentistry College, Mustansiriyah University, Baghdad, Iraq
3BSc, H.D.D. MSc. Dentistry College, Mustansiriyah University, Baghdad, Iraq
The fluctuating levels of sex hormones throughout menopause have an influence on oral health and periodontal disease. Deficiency of sex hormone during menopause and aging process mostly associated with local tissue and salivary flow changes make oral tissue more prone for infection. Few studies that assessed the rate of oral herpes simplex infection, bacterial growth and rate of gingivitis among postmenopausal women receiving Hormonal Replacement Therapy. So aims Of study to assess the association of using the HRT and the incidence and recurrence rate of oral HSV infection, bacterial growth and gingivitis among post-menopausal women.
A cross sectional study carried out between 1st.oct.2017-1st. May 2018. Participants selected from private and outpatients’ clinics of Dentistry College of Mustansiriyah University. Fifty-eight women in post-menopausal phase were selected randomly and categorized to two groups according to using the HRT. Frequency, severity of herpes simplex, relation of recurrence status to duration of using HRT, gingival index and bacterial growth were analyzed.
Proportion of participants had mild, moderate and sever herpes simplex infection were 36.2, 34.5, 29.3% respectively. Proportion of subjects who are receiving HRT that reported sever herpes simplex infection and recurrence rate of >8 per year was significantly lower in comparison to non-user (18.4 vs.50%), (13.2 vs.45%) respectively. No significant association was found between severity or recurrence rate of HSV infection and duration of HRT use. Significant lower gingival index (GI) and bacterial growth (p=0.01 for all) with women who were on HRT (1.6 vs.2.8), (74.5 vs.127.3) respectively. The mixed bacterial isolate was reported with 55.2% of participants but no significant association found between type of isolate and status of using HRT and recurrence of HSV infection, in addition it has impact on gingival health of post-menopausal women
Herpes simplex infection, Hormonal Replacement Therapy, post-menapouse
