1Research Scholar, Department of Nanotechnology, Noorul Islam Center for Higher Education, Kumarakovil, Kumaracoil, Thuckalay, Tamilnadu, India
2Assistant Professor, Department of Biotechnology, Sri Sankara Arts and Science College, Ernathur, Kanchipuram, Tamilnadu, India
3Professor, Head of the Department Department of Nanotechnology, Noorul Islam Center for Higher Education, Kumarakovil, Kumaracoil, Thuckalay, Tamilnadu, India
*Corresponding Author: P. K. Praseetha, Professor, Head of the Department, Department of Nanotechnology, Noorul Islam Center for Higher Education, Kumarakovil, Kumaracoil-629180, Thuckalay, Tamilnadu, India, Email: crkpkp@gmail.com
Online published on 19 August, 2019.
Bioactive compounds from herbal plants possess a wide range of pharmaceutical activities and one among them is Myristica fragrans (Nutmeg).
Antibacterial screening of the different solvent extracted phytoconstituents showed maximum growth inhibitory effect against E.coli and S. mutans. Agar well diffusion sensitivity testing method was adopted for this study.
Acetone extract of the seeds also performed good bactericidal effect against the bacterial pathogens.
MTT assay also demonstrated good cytotoxic effect against MCF-7 cell lines in a dose-dependent manner with inhibitory concentration (IC50) achieved at 62.5 μg/mL.
Based on the findings of the study, seeds of Myristica fragrans could be exploited in developing potential bioactive pharmaceutical drugs for effective treatment of cancer.
Myristica fragrans Anti bacterial MTT assay Cytotoxicity
