Indian Journal of Public Health Research & Development

There are number of non-protein amino acids of plant origin considered as neuro-toxic source& pose serious health hazards both to human and animals.

This Research was designed to studythe natural toxin present in Lathyrus sativus (Grass Pea) that resulted from the neurotoxic amino acids in Lathyrus seeds which are very important because they are of immediate relevance to human health or diseases affecting domestic animals, and they have resulted in findings of several unusual and novel mechanisms of biosynthesis and metabolism.

This research study the toxicity of ODAP and the incidence of neurolathyrism, estimate the concentration of ODAP in seeds, estimate qualitatively the presence of ODAP and DAP in Lathyrus seeds and estimate the protease activity in growing seedlings of Lathyrus.

The results showed that ODAP had inhibitory effect on the growth of the microorganism Pseudomonas indica. However, it showed very little inhibition on E. coli and showed no effect on the others like Klebsiella, Pseudomonas aeruginosa, Staphylococcus aureus