Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 8

Estimation of Serum Fasting Insulin in Patients with Acne Vulgaris and Compares these Values with that in Controls

  • Author:
  • Archana Chaudhary1, Urender Singh2, MPS Sawhney3, Busi Karunanand4, Bhupinder Kaur Anand5,, Marwaha Manvinder Pal Singh6
  • Total Page Count: 6
  • Page Number: 666 to 671

1Associate Professor, Department of Environmental Science, Faculty of Science, SGT University, Gurugram, Haryana, India

2Additional Sr. Medical Officer, Civil Hospital, Bhiwani

3Professor, Department of Dermatology & Venereology, SSGT Medical College, Hospital and Research Institute, Gurugram, Haryana, India

4Professor, Department of Biochemistry, SSGT Medical College, Hospital and Research Institute, Gurugram, Haryana, India

5Professor, Department of Community Medicine, SSGT Medical College, Hospital and Research Institute, Gurugram, Haryana, India

6Classified Specialist Aerospace Medicine, Air Force Central Medical Establishment, New Delhi, India

*Corresponding Author: Bhupinder Kaur Anand, Professor, Department of Community Medicine, SGT Medical University, Gurugram, Haryana, India Email: dr.medical.123@gmail.com

Online published on 26 September, 2019.

Abstract

Acne is a multifactorial inflammatory disease affecting the pilosebaceous follicles of the skin. Acne is a disorder resulting from the effect of hormones and other substances on the oil glands (sebaceous glands) and hair follicles present in the skin. The aim of this study was estimation of serum Fasting insulin in patients with acne vulgaris and compares these values with those in controls.

This is the case control study which was carried out in the Departments of Biochemistry and Dermatology & Venereology of SGT Medical College Gurgaon. Fifty patients each of Mild (group I), Moderate (group II) and Severe Acne Vulgaris (group III) in age group 15–40 years were included as cases.

In the present study, the level of serum insulin was significantly higher in moderate cases of acne as compared to controls. Therefore we suggest that insulin may also play an important marker for causing acne. Insulin stimulates the secretion of ovarian estrogen, androgen and progesterone which is consistent with our studies as increase in estrogen and testosterone has been also observed in moderate cases of acne.

Insulin was significantly higher in moderate cases as compared to controls. There by suggesting that insulin may play an important role to causation of acne.

Keywords

Insulin, acne vulgaris, multifactorial inflammatory disease