Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 8

Serum Levels of IL-12 Family in Hepatitis Patients with HBV and HCV Infections

1Department of Biology, Madenat Al-elem University College, Baghdad, Iraq

2Ministry of Science and Technology, Baghdad, Iraq

*Corresponding author: Osama B. Al-Saffar, E-mail: Osamaalsaffar@gmail.com

Online published on 26 September, 2019.

Abstract

Hepatitis is inflammation of the liver, with hepatitis, the liver not working well. Viruses one of the most causes of hepatitis in the world. Cytokines are small proteins produced by cells have a specific interaction effect on the connection between the component of the immune system. Therefore, the present study aimed to investigate the serum level of the interleukin-12 family is a unique cytokines in comprising the heterodimeric, includes (interleukin-12, interleukin-23, interleukin-27, and interleukin-35). All investigated cytokines (IL-12, IL-23, IL-27, and IL-35) showed significant variations. Serum level of interleukin-12 and interleukin-23 showed a significant difference in viral hepatitis patients compared to controls according to age group. Distribution patients and controls into males and females revealed some significant differences in the serum level of the interleukin-12, interleukin-27, and interleukin-35.

Keywords

Serum level, IL-12 family, HBV, HCV, Iraqi Patients