1Department of Ear, Nose, Throat, Head-Neck Surgery, Medical Faculty, Hasanuddin University, Makassar, Indonesia
2Departement of Statistic, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
Online published on 26 September, 2019.
The research aimed to perceive the comparison of inflammation response (IL-33 and eosinophil contents) in chronic rhinosinusitis with nasal polyp and without nasal polyp, and the pathomechanism of nasal polyp incident on chronic rhinosinusitis.
This was the cross sectional research with 40 patients. Each sample underwent IL-33 serum content examination, and nasal mucosa swab.
The research result indicates that IL-33 serum contents were significantly higher (p <0.05) in patients with Chronic Rhinosinusitis without Nasal polyp than with Nasal polyps, While the number of eosinophils content in chronic rhinosinusitis with nasal polyps was significantly higher (p <0.05) than without nasal polyps
IL-33 has higher content on chronic rhinosinusitis without nasal polyp, IL-33 increases eosinophil content in chronic rhinosinusitis without nasal polyp, and the eosinophil has higher content on chronic rhinosinusitis with nasal polyp.
Chronic Rhinosinusitis, Nasal polyp, Interleukin 33, Eosinophil
