1College of Science, University of Babylon, Iraq
2College of Basic Education, University of Babylon, Iraq
3Omar Al-Mukhtar University, El-Gubba
*Corresponding Author: Mona N. Al-Terehi, College of Science, University of Babylon, Iraq Email: Monanajah1981@gmail.com
Online published on 26 September, 2019.
Vitiligo have been recorded in different ages in population it is appeared by interaction between different factors causes de-pigmentation in skin, the present study conducted to estimate HLA 27 gene polymorphism in vitiligo patients using single specific primer-polymerase chain reaction (PCR-SSP), DNA was extracted from whole blood for patients and control, then amplification was implemented, the results of demographic show that the means of age were 33.093 and 32.809 for patients and control, disease was recorded in female than male 79.54%, 18.18%, about 36.36% of patient had family history and56.81% of them, their parents had family related. High percentage of patients had dispersive sites of de-pigment sites 54.54% while 40.90% of them in hands and legs. The genotyping results show that there was no association between HLA B27 and vitiligo disease, HLA-was 95.83% in patients while it was 85.71% in control in non-significant differences
This study concluded that there was no association between HLA B 27 and vitiligi disease in Iraqi population.
Vitiligo disease, of Human Leukocyte Antigen-(HLA-B 27), PCR-SSP
