Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 8

The Incidence of Breast Cancer in Women with Thyroid Dysfunction in Al-Najaf Province

  • Author:
  • Zainab S. Mohammed1,, Radhwan M. Hussein1, Alaa A. Ali1, Hasanain J. Kadhim2
  • Total Page Count: 7
  • Page Number: 2316 to 2322

1College of Pharmacy, Ahl Al-bait University, Kerbala, Iraq

2Pathological Analysis Techniques Department, AL Tousi University College, Najaf, Iraq

*Corresponding Author: Zainab S. Mohammed, College of Pharmacy, Ahl Al-bait University, Kerbala, Iraq, Email: zainebsajidnajaf@yahoo.com

Online published on 26 September, 2019.

Abstract

The problem of B.C. is growing in both established and developing states, and in many provinces of the domain, it is the utmost frequently arising malignant sickness in females; it is including (18 percent) from the all cancers that effected woman, and the global, B.C. is the 5th greatest public cause of death with cancer. In year (2008), almost (1.4) m. female were established with B.C.in universal with a consistent about (460.000) demises.

Thirty Participants were included in this study; they were attendants of Al-Sadder Medical City, breast cancer unit and Middle Euphrates Cancer Center in AL-Najaf province.

The results of the present study revealed positive family history of breast cancer in 60% of malignant cases, while negative cases comprise 40%. In benign cases; positive family history was less frequent comprises only (26%) while negative cases was of higher frequency (73%), and such difference was highly significant (P ˂ 0.05).

A.B.O. blood group phenotypes in B.C. female patients in both type malignant, and benign and healthy woman (married, single and infertile women) revealed no insignificant alteration, where as an improved incidence of blood group phenotype B (64%), and a decreased frequency of blood group AB (10%) in evil (malignant) unhealthy person as matched with healthy assemblies, infertile, solitary, wedded (30%, 30%, 22% independently), and however an improved frequency of blood group O (43%) and a decreased frequency of blood group A (13%) in benign patients as compared with control groups infertile, solitary, married.

The present research advocated an elevation occurrence of goiter synchronized with extraordinary frequency of autoimmune thyroiditis, established mainly by A.b. positivity, in woman breast cancer persons. Hyperthyroidism was found in high percentage 6 cases (20%) in malignant breast cancer and 4 cases (10%) in benign cases when compared with control group 1 (4.0%), (P˂0.05). The present study revealed high percentage of hypothyroidism, Nontoxic goiter was found in 20 patients in malignant breast cancer group (67%) and 23 in benign breast cancer patients (77%) controls 6 (96%) and such difference was highly significant (P ˂ 0.05).

Keywords

Brest cancer, thyroid, Najaf