Comparative Study for the Diagnostic Features of BNP and HS-CRP in Patient with Heart Failure

A large number of diagnostic tests are used to confirm the presence of heart failure (HF) disease including symptoms and clinical signs of HF, radiological examinations, echocardiography, electrocardiography and laboratory blood tests. Also in recent years, in 1988, a new cardiac natriuretic peptide [B-type natriuretic peptide (BNP)] with excellent diagnostic characteristics was discovered. Wherefore, in the next years was appeared to have prognostic properties and later likewise seemed to have symptomatic properties in the out patient settings and emergency department.

In this research we completed work with participants, part of them patients with heart failure to varying degrees and another part do not suffer from heart failure to be a control group on which to build the results of the research. We pulled the blood from them, turned it to serum, estimated concentrations of certain chemical agents that are under research such as (BNP, hs-CRP, T-Chol, HDL-cholesterol, TG, LDL-cholesterol and VLDL-cholesterol) and compared these concentrations with another factor (EF %). Generally, we found a clear increase in concentrations of BNP and hs-CRP (Percentage increase in BNP and hs-CRP concentration level is estimated at 497%, 332% which is 5, 3.32 times as much as the BNP and hs-CRP concentration in control group D respectively), with the greater decline in the value of EF%. As well as compared to other factors (Percentage increase in T-Chol, TG, LDL-cholesterol, VLDL-cholesterol and percentage decrease in HDL-cholesterol,). Therefore, the BNP and hs-CRP are the two best factors of the total factors studied in the research to diagnose heart failure disease.