1Department of Physiology and Medical Physics, College of Medicine, University of Babylon, Babylon, Iraq
2Department of Physics, College of Science, University of Baghdad, Baghdad, Iraq
*Corresponding Author: Entidhar J. K. AL-Taee, Department of Physiology and Medical Physics, College of Medicine, University of Babylon, Babylon, Iraq, Email: Intdher071@gmail.com
Online published on 26 September, 2019.
Nanotechnology is a discipline that manages, constructs, analyzes and deals with application of materials that have diameter from 1 to 100 nanometers. Gold nanoparticles are defined as stable colloid solutions of clusters of gold atoms with sizes at this minuscule.
The objective of current study was to treat breast cancer using gold nanoparticles capped with drug molecules in specific quantities to reduce the harmful side effects.
The gold nanoparticales were prepared by method of Brust-Schiffrin. These nanoparticles were capped with type of drug (Glutathione) used to treat cancerous tumors. These gold nanoparticles were uncapped with drugs at (526nm) when capped with the glutathione drug at (589nm).
The resulting evidence suggested that Glutathione-capped Gold nanoparticles were non-toxic up to the maximum recommended dosage. Therefore, the demonstrated biocompatibility offers the potentials of Glutathione-capped with Gold nanoparticles. The candidate is considered as a medicine for cancer therapy.
Gold nanoparticles, PDT, MCF-7 cell, glutathione, breast cancer
