Indian Journal of Public Health Research & Development

  • Year: 2019
  • Volume: 10
  • Issue: 9

Firmicutes-The Lesser Known Flora Playing Greater Roles in Periodontitis

1Professor, Department of Periodontics

2Professor & HOD, Department of Microbiology

3Professor, Department of Periodontics

4Assistant Professor, Department of Epidemiology

Abstract

In the complex issue of oral microbiome, the clear floral recipe for periodontitis is yet a unachieved milestone. Lesser known species are being associated with periodontal lesions. The role of Firmicutes is still not completely described.

To identify and explore the role of clinically significant Firmicutes in chronic and aggressive presentations of periodontal lesions.

Subgingival plaque samples were isolated from six patients (three chronic and three aggressive lesions) and metagenomics was performed. Those Firmicutes that differed significantly were identified and discussed.

Firmicutes as thought earlier are not insignificant and have great potential in periodontal dysbiota. Molecular pathways have to be determined to aid in arriving at a floral recipe for periodontitis.

Keywords

Firmicutes, Metagenomics, Periodontitis