Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 9

The Alcoholic Extract of carrot (Daucus carota L.) Seeds as Antioxidant in Male Albino Mice Treated with H2O2

1The National Center of Hematology. Al-mustansiriyah University. Iraq

2Department of Biology, College of Sciences for Women, University of Baghdad

3Biotechnology Applications College, Al-Nahrain University

Online published on 13 November, 2019.

Abstract

This study was designed to research activity Daucus carota seeds alcoholic extract on the fertility of male albino mice that treated with H2O2 by changing the body weight, testis, secondary sex organ weights and sperm parameter and hormonal changes (Testosterone, FSH, and LH). This experiment used thirty-two (8–10) weeks’ old albino male mice. These mice were separated into four sets; the first negative group was given physiological saline, the second group was given the alcoholic extract (400mg\kg), the third group was given H2O2 (0.05%) in the drinking water, the fourth group was given both H2O2 (0.05%) and the alcoholic extract (400mg\kg) during (35) days. The results showed: The third group (H2O2) showed significant (P<0.05) decrease the weight of bodies, and significant (P<0.05) increase in testes, prostate and seminal vesicle weights by comparing with control and second group. The result shows a significant decrease in ratios of motility, live sperms and sperm concentration. Also, the concentration of Testosterone, FSH and LH show a significant reduction in the first group when equated with control. While fourth group (H2O2 (0.05%) and the alcoholic extract (400mg\kg) gave significant increase in weights of body and testes, prostate, seminal vesicle weight; this group gave results nearly that in control group result in all reproductive parameters such as hormones concentration, sperms motility and concentration so that the alcoholic extract could provide protection for oxidative stress of H2O2.

Keywords

Carrot seeds, sperm parameters, sex hormones, Hydrogen peroxide