Pulmonary Medicine, Rajiv Gandhi Institute of Medical Sciences Adilabad 504001, A.P.
*Correspondence: Dr. Md. Aleemuddin Naveed, 20-5-115/A Shahlibunda Hyderabad-500065, Andhra Pradesh. India. aleem95@yahoo.com, 09949671249, 04024574776.
Isoniazid (INH) is most frequently used in combination with other drugs for the treatment of tuberculosis or as monotherapy for treatment of latent tuberculous infection. Seizures due to anti-tubercular chemotherapy are a rare side effect. INH causing status epilepticus has been very rarely reported to cause seizures. We present a patient who, after 5 months of treatment with appropriate dose of INH, evolved to status epilepticus. Seizures could be controlled only after administering of pyridoxine.
Isoniazid, Acute neurotoxicity, Status epilepticus, Seizures, Pyridoxine
