RIMS Medical College, Kadapa-516002, A.P, India
Online published on 23 January, 2012.
Human spleen is an organ of anatomic and functional component of reticuloendothelial system. Spleen is situated in left hypochondrial region. It is soft friable, highly vascular and dark purple in colour. Histogenesis of spleen Studied in 50 fetuses of various gestational ages ranging from 11weeks to 38weeks.
By 11th week only lymphocytic aggregation seen.
By 20th week developing lymphoid follicles observed.
By 32 weeks well developed lymphoid follicles with central arteriole seen.
At 36 weeks crack at periphery of developing lymphoid follicles and arteriole is at periphery.
Lymphoid aggregation, lymphoid follicles, central arteriole, Histogenesis, White pulp
