Congenital malformations detected at birth – A prospectivestudy in Bangalore

In a prospective study of 4280 births in Vanivilas Hospital, Bangalore Medical College, Bangalore 61 cases of congenital malformations were observed with an Incidence of 14.25/1000 live births. A total of 117 malformations were observed. Among these 95 were major and 22 were of minor type. The central nervous system, gastro-intestinal and multiple system involvement were the commonest with 12 cases each (19.67%), followed by musculoskeletal 11 (18.03%), cardio-vascular 4 (6.56%), genito urinary 02 (3.30%)cases), cutaneous 1 (1.64%) and 07 (11.49%) cases were miscellaneous. Malformations in the new born males were 52.46%, in females it was 45.90% and 1.64% are of ambiguous genitalia thereby showing male preponderance. Maximum of 42 cases (68.85%) were born to non-consanguineous group and 19 cases (31.15%) were to consanguineous couples.