1Department of Biochemistry, Navodaya Medical College, Raichur, Karnataka
2Department of Biochemistry, KMC, Manipal University, Mangalore, Karnataka
3Department of Biochemistry, VIMS, Bellary, Karnataka
4Department of Biochemistry, FMMC, Kankanadi, Mangalore, Karnataka
5Department of Anatomy, KSHEMA, Nitte University, Mangalore, Karnataka
6Department of Biochemistry, Navodaya Medical College, Raichur, Karnataka
Online published on 1 June, 2012.
The level of gamma glutamye transpeptidase (GGTP or GGT) is especifically increased in alcoholic liver diseases with biliary obstruction. There are many other diseases where alterations in the level of GGTP are noted. Hence, the study was aimed to estimate the level of GGTP in smokers and congestive cardiac failure (CCF) patients along with total cholesterol (TC).
35 each clinically diagnosed CCF patients, smokers and normal healthy male subjects were included in the study. GGTP was estimated by enzymatic colorimetric method and total cholesterol by cholesterol oxidase peroxidase method using P-800 chemistry antoanalyser. Statistical analysis was done using ANOVA.
The GGTP and TC levels were significantly (p<0.001) increased in the both CCF patients and smokers but increase is more significant in CCF patients.
GGTP can be used as a potential biomarker along with total cholesterol in cardiovascular diseases especially CCF because of their direct relationship with the indication of atherogenesis.
GGTP, TC, CCF, Smokers
