Indian Journal of Public Health Research & Development

  • Year: 2012
  • Volume: 3
  • Issue: 4

Prostate-Specific Antigen Variations in Moroccan Patients with Histologically Proven Benign Prostatic Hyperplasia

  • Author:
  • I. Sadaoui1,2, H.A.H. Joutei2, N. Elgnaoui2, A. Seddiki3, S. Nadifi1, H. Benomar2
  • Total Page Count: 4
  • DOI:
  • Page Number: 128 to 131

1Department of Medical Genetics Faculty of Medicine and Pharmacy, Casablanca, Morocco

2Department of Anatomic, Pathology of Pasteur Institute, Casablanca, Morocco

3Department of Urology of Racine Center, Casablanca, Morocco

Abstract

Benign prostatic hyperplasia (BPH) is the most common benign disease of prostate gland and it has a great prevalence in aged men; however, the effect of benign prostatic hyperplasia (BPH) on PSA level is less well understood.

In order to improve the ability of PSA to distinguish cancer from BPH, it is necessary to understand the characteristics of PSA in a population of men without prostate cancer. Because of the increase in the aging male population in Morocco, the role of PSA in the assessment of patients with BPH and lower urinary tract symptoms (LUTS) should be examined.

We examined whether there was a relationship among the serum PSA level, weight of resection, prostate inflammation and patient's age to estimate clinical implication of the PSA on diagnosis and treatment of BPH.

Our results indicated that PSA level is statistically correlated with age and weight of resection and subclinical prostatic inflammation could be the etiology of an elevated serum PSA in men with benign prostatic hyperplasia.

Keywords

PSA, Benign prostatic hyperplasia, subclinical prostatic Inflammation