1Assistant Professor, Department of pathology. Sri Siddhartha Medical College, Tumkur
2Associate Professor, Department of pathology. Sri Siddhartha Medical College, Tumkur
3Professor and Head of the Department, Department of pathology. Sri Siddhartha Medical College, Tumkur
Online published on 19 November, 2012.
Hypertensive disorders of pregnancy have some definite adverse influence on the morphology of the placenta and growth of the fetus. The placental changes are more prominent with increased severity of the disease process. Of the 100 placentas, 29 placentas were from normal pregnancy, 42 placentas were from mild preeclampsia, 18 placentas were from severe preeclampsia and 11 from eclampsia.
The incidence of eclampsia is common in primigravida. Mean weight of placenta and mean birth weight of the fetus were decreasing with increasing grades of hypertension. The mean diameter of placenta and mean number of cotyledons were reduced with increasing grades of hypertension. The syncytial knot formation, hypervascularity, fibrinoid necrosis of villi, fibrosed villi and basement membrane thickening were seen predominantly in pregnancy induced hypertension.
Placenta, Pregnancy induced hypertension, Syncytial knot, Hypervascularity