1Assistant professor, Department of Anaesthesiology, Navodaya medical college, Raichur,
2Professor and HOD, Department of Anaesthesiology and pain palliative care, Sapthagiri institute of medical science and research centre, Bangalore
Online published on 19 November, 2012.
To compare the success rate, suitability, airway reflexes and hemodynamic changes between propofol versus thiopentone with lignocaine spray for LMA insertion.
A study conducted on 100 ASA grade I or II patients aged 18–60 years scheduled for elective surgery for which an LMA was appropriate, were randomly allocated in to two groups, received diazepam 0.2 mg/Kg IV and atropine 0.6 mg IV 3 minutes before induction. Group-1 received propofol 2.5 mg/Kg IV (n=50). Group-2 received 30 mg of topical lignocaine spray to posterior pharyngeal wall, 3 minutes prior to thiopentone 5 mg/Kg IV (n=50). All patients were preoxygenated for 3 minutes before the induction of anesthesia. Adverse responses (gagging, coughing, and laryngospasm, movement of head and limb, inadequate jaw relaxation), severity of reaction (mild, moderate and severe) and overall reaction were recorded and graded. Hemodynamic changes were recorded and compared.
There was no significant difference between the two groups with regard to adverse responses, severity, overall reaction, pulse rate and diastolic blood pressure (p>0.05). The fall in systolic blood pressure was significantly greater with propofol than thiopentone (p<0.01).
Thiopentone preceded by lignocaine spray provided equal condition as of propofol for insertion of LMA with more hemodynamic stability.
Intravenous, Thiopentone, Propofol, Laryngeal mask airway (LMA), Lignocaine/Lidocaine 10% aerosol spray
