1Professor and Head, Dept of Biochemistry, Saraswathi Institute of Medical Sciences, Hapur (UP)
2Professor and Head Dept of Biochemistry, SBH Govt. Medical College, Dhule (Maharashtra)
3Associate Professor, Dept of Biochemistry, L T M Medical College & Hospital, Sion, Mumbai (Maharashtra)
*Corresponding author: Mane A. Y., Associate professor, Department of Biochemistry, Saraswathi Institute of Medical Sciences Pilkhuwa, Hapur, Dist Gaziabad (UP), Phone no: 09690229114, E-mail: aymane@rediffmail.com
Online published on 13 February, 2013.
Cement used in building and various construction works is a complex mixture of several metal oxides, silicates and miscellaneous compounds. In India, laborers involved in construction work are constantly exposed to the cement various ways. Biochemical effects of the occupational exposure in 31 workers were assessed by Aspartate transaminase, Alanine transaminase, Calcium, Magnesium, Maolondialdehyde and Ascorbate levels in serum. It was found that serum ALT, AST and calcium levels were elevated as compared to the controls. The Dirties ratio was significantly higher in the workers. The lipid peroxidation index was higher while ascorbate level was significantly lower in the cases. It is concluded that the construction worker show marginal alteration in liver functions which is secondary to oxidative stress generated by complex interaction of toxic cement compounds.
Cement, Alanine transaminase, Aspartate transaminase, Calcium Magnesium, Maolondialdehyde and Ascorbic acid
