1Associate Professor Cum HOD, Dept of Biochemistry, VCSG Govt Medical Science & Research Institute, Srikot, Srinagar (Pauri), Uttarakhand, India
2Assistant Professor, Dept of Community Medicine, VCSG Govt Medical Science & Research Institute, Srikot, Srinagar (Pauri), Uttarakhand, India
3Assistant Professor, Dept of Biochemistry, VCSG Govt Medical Science & Research Institute, Srikot, Srinagar (Pauri), Uttarakhand, India
Online published on 16 May, 2013.
Pregnancy is associated with significant but reversible changes in thyroid function tests which are among the most profound to be seen as a result of a normal physiologic state. As regards with thyroid hormone levels, the pregnancy is a state of thyroid hyper-stimulation, leading to increase thyroid hormone levels. The common thyroid diseases during pregnancy are hypothyroidism, hyperthyroidism and postpartum thyroiditis. Our study was to elucidate the role of these hormones during pregnancy in Garhwal region, India.
The thyroid function tests were carried out by measuring serum levels of thyroid stimulating hormone (TSH), free thyroxine (FT4) and free triiodothyronine (FT3) by ELISA technique in randomly selected 50 pregnant women and 50 non-pregnant healthy women in the age group of 15 - 45 years to find out the alteration in thyroid function tests. Results were calculated by using student's t-test and 0.05 level of significance.
It is found that the mean FT4 and TSH values are significantly decreased (<0.05 in both cases) and FT3 level increased (>0.05) during pregnancy as compare to the non- pregnant women.
Pregnancy, Free Thyroxine (FT4), Free Triiodothyronine (FT3), Thyroid Stimulating Hormone (TSH), Thyroid Function Test
