Indian Journal of Public Health Research & Development
  • Year: 2013
  • Volume: 4
  • Issue: 2

Correlation of C-Reactive Protein with Body Mass Index and Blood Pressure in Young Adult North Indian Hypertensive Males -A Prospective Study

  • Author:
  • Kiran Singh1,, Anita Pandey2, Tanuraj Sirohi3, Rajesh Misra4, Rupesh Tewari5
  • Total Page Count: 5
  • Page Number: 134 to 138

1Professor, Department of Physiology, Subharti Medical College, Meerut

2Professor, Department of Microbiology, Subharti Medical College, Meerut

3Professor, Department of Medicine, Subharti Medical College, Meerut

4Professor and Head Department of Physiology, Subharti Medical College, Meerut

5Lecturer, Department of Biostatistics, Subharti Medical College, Meerut

*Corresponding author: Kiran Singh, Department of Physiology, Subharti Medical College, N H-58 Meerut-250005, E-mail: singhkiran15@yahoo.co.in, Mob: 09410886644

Online published on 16 May, 2013.

Abstract

High blood pressure has been associated with elevated C-reactive protein (CRP), a possible marker of vascular inflammation. The aim of this study was to assess the interrelationship between blood pressure and CRP in young adult north Indian males.

A total of 30 patients with mild to moderate essential hypertension in the age group of 2540 years were enrolled for the study. Patients with history of secondary or malignant hypertension were excluded. Age and sex matched healthy normotensive subjects (n=35) were taken as control. The parameters studied were BMI, Systolic (SBP), diastolic (DBP) blood pressure and CRP. C-reactive protein was measured by RHELAX CRP slide test. Statistical analysis was done by using Karl-Pearson correlation coefficient and Student's unpaired t test.

We have observed significant differences (P<0.05) in BMI, SBP and DBP between the study and control groups. The study reveales a significant correlation (p<0.01) between BMI and blood pressure and a positive non-significant (p>0.01) association between blood pressure and CRP levels in the study group.

Further studies are needed to explore the relationship between blood pressure and CRP using highly sensitive assays as a major screening test in the prediction, diagnosis and management of essential hypertension.

Keywords

BMI, Blood Pressure, C-reactive protein, Young Indian Adults