1Asst.Professor, Pathology, School of Medical Sciences & Research, Sharda Hospital, Greater Noida, U.P.
2Professor, Pathology, School of Medical Sciences & Research, Sharda Hospital, Greater Noida, U.P.
3Consultant Pediatrician in Ghaziabad & Greater Noida
Blood transfusion is an effective mode of transmission of hepatitis C infection. In developed countries various measures have been taken to reduce the spread of infection through this route. In India, mandatory screening for HCV was introduced as late as 2002 though it was started in Japan & US in 1990. Still, the studies all over India suggest that despite testing of blood units HCV infection is still a significant problem.
HCV is transmitted by blood to blood contact. In developing countries about 90 % of persons with chronic HCV were infected through transfusion of unscreened blood or blood products or via intravenous drug abuse or sexual exposure. Also, in developing countries, the primary sources of HCV infection may be unsterilized injection equipment.
The present study was conducted to find out seroprevalence of hepatitis C in 6000 donors in greater noida. The screening was done by ELISA third generation microelisa kit.
Seroprevalence of anti HCV in 6000 donors was 1.28 % with the prevalence of 1.34 % in voluntary & of 1.28% in replacement donors.
Males show higher incidence of 1.29% & females 0.66 %.
Blood group B negative showed higher positivity (1.886%) followed by A positive (1.408%) closely followed by O positive (1.4008%).
Age group >51 yrs show positivity of 5.405% followed by age group of 31-40 yrs (1.745 %).
HCV- hepatitis - C virus, seroprevalence, Blood Donors, ELISA
