Posterior Reversible Encephalopathy Syndrome (PRES) Following Disulfiram Intoxication - A Case Report

Posterior reversible encephalopathy syndrome (PRES) also known as reversible posterior leukoencephalopathy (RPLS) is a syndrome characterized by headache, confusion, seizures and visual loss. It may occur due to a number of causes, predominantly malignant hypertension, ecclampsia and some medical treatments.

We present a case of PRES due to disulfiram intoxication in a chronic alcoholic patient. The condition was diagnosed on MRI which showed the typical radiological features. The patient recovered completely with complete reversal of radiological changes after the causative agent disulfiram was discontinued.