1Assistant Professor, Department of Biochemistry, J.J.M.Medical College, Davangere, Karnataka
2Post graduate, Department of Biochemistry, J.J.M.Medical College, Davangere, Karnataka
3Assistant Professor, Department of Biochemistry, Krishna Institute of Medical Science, Karad, Maharashtra
The association between established hypothyroidism and high cholesterol level is well known. The aim of the present study in to assess the association of thyroid hormones with serum lipids in hypothyroidism patients compared with normal person.
The study included 30 diagnosed hypothyroid patients between the age group of 20–60 years as cases and 30 age and sex matched normal person as controls.
Hypothyroid patients had an increase in total cholesterol, Triglycerides and LDL cholesterol when compared to normal persons. Statistical analysis showed a significant correlation between raised TSH levels and serum total cholesterol and LDL cholesterol levels (p < 0.001).
Serum lipids abnormalities might be a potential link between hypothyroidism and Atherosclerosis.
Hypothyroidism, TSH, Lipid Profile, Atherosclerosis