Indian Journal of Public Health Research & Development
  • Year: 2015
  • Volume: 6
  • Issue: 1

Study of Clinical Profile, Complications and Response to Treatment of Enteric Fever Cases Admitted in a Tertiary Care Hospital of Solapur

1Assistant Professor, Dept. of P.S.M, B.J. Govt. Medical College, Pune

2Professor, Dept. of Community Medicine, K.I.M.S., Karad

3Dean, Ashwini Rural Medical College, Hospital and Research Centre, Kumbhari, Solapur, Maharashtra

4Medical officers, PHC-Kashti, Tal-Shrigondha, Dist-Ahmadnagar

*Correspondence: Dr. Parande Malangori Abdulgani, 462/C-2, Greenland Complex, Salisbury Park, Gultekdi, Pune-411037, State: Maharashtra. Mobile no.- 09850131337, 09881947880, E-mail address: drparandemalan@rediffmail.com.

Online published on 13 January, 2015.

Abstract

Widespread and indiscriminate use of anti-microbials and anti-pyretics in enteric fever contributes to the development of some unusual or atypical presentations in our country. So it's important to assess the current clinical presentations, complications and prognosis of enteric fever cases.

i) To study clinical profile and laboratory manifestations of enteric fever cases ii) To study trends, response to antibiotics, complications and prognosis of enteric fever cases.

A hospital based cross-sectional descriptive study was conducted from January to December. All proved cases of enteric fever admitted in medicine and pediatric ward of SCSMGH, Solapur were the study subjects. Total 172 cases of enteric fever were admitted during this period.

Simple proportions

Majority of patients were in 11–20 years (school children and adolescents) age group. Majority of the cases occurred in rainy season. Common clinical features of enteric fever include fever, tachycardia, hepatomegaly and splenomegaly. Relative bradycardia and rose spots considered to be salient features of enteric fever were infrequently seen in our study. More than half of the cases (51.2%) presented during first week of illness. Widal test might be regarded as an important diagnostic tool for enteric fever in strongly suspected cases. Ciprofloxacin was the most commonly used antibiotic in our study. Time to defervescence for patients treated with ciprofloxacin was 5.3 days and that for Third generation cephalosporins was 4.8 days. The proportion of complication was 51(29.65%). Out of 172 respondents, three patients (1.74%) died, 2(1.2%) due to intestinal hemorrhage and 1(0.6%) due to disseminated intravascular coagulation (DIC) and 18(10.5%) lost to follow up and remaining all recovered completely.

Changing paern of fever and atypical presentation of enteric fever should be borne in mind so that an early diagnosis can be made to initiate appropriate therapy and thereby reducing mortality.

Keywords

Enteric fever, time to defervescence