1Professor & Head of the Department, Oral Pathology, Microbiology & Forensic Odontology, Government Dental College & Hospital, Ahmedabad
2Post Graduate Student, Oral Pathology, Microbiology & Forensic Odontology, Government Dental College & Hospital, Ahmedabad
3Senior Lecturer, Surendera Dental College & Research Institute, Sri Ganganagar, Rajasthan
4Bachelore of Dental Surgery, Pasific Dental College and Hospital, Rajasthan
*Corresponding Author: Dr Pratik Rupakar, Post Graduate Student, Oral Pathology, Microbiology & Forensic Odontology, Government Dental College & Hospital, Ahmedabad. Address: 22, Shiv Darshan Bunglows, Por-kudasan Road, Kudasan, Gandhinagar-382421. Gujarat
Online published on 13 January, 2015.
The ABO blood type, an easily accessible factor in patient's genetic makeup, has been associated with many diseases.
To investigate the association between oral cancers and ABO blood groups.
In the present study 108 patients of histopathologically diagnosed oral squamous cell carcinoma and 1000 individuals with habit of tobacco chewing were included with their blood groups.
Blood group A and B individuals in their 4th and 5th decades of life were more susceptible to oral cancer which is statistically significant. Patients of well differentiated squamous cell carcinoma were predominantly in B blood group and moderately differentiated were in A blood group which is statistically highly significant. Tobacco chewing habit was predominant in B blood group individuals followed by A, O and least in AB blood group individuals.
Tobacco chewing habit was predominant in males of Gujarat state, India and individuals with blood group B were more prone to tobacco chewing habit and oral squamous cell carcinoma in their 4th to 6th decades of life. Buccal mucosa was the predominantly affected site in B blood group individuals followed by O blood group individuals, which suggested genetic susceptibility in oral squamous cell carcinoma.
ABO Blood-Group, Buccal Mucosa, Genetic, Oral Squamous Cell Carcinoma, Tobacco
