1Senior Resident, Dept. of Anaesthesiology, Raichur Institute of Medical Sciences, Raichur, Karnataka
2Senior Resident, Dept. of Orthopaedics, Navodaya Medical College, Raichur, Karnataka
3Associate Professor, Dept. of Pathology, Navodaya Medical College, Raichur, Karnataka
4Dept. of Pschyiatry, Navodaya Medical College, Raichur, Karnataka
*Corresponding author: Vishalakshi Patil, Senior Resident, Dept. of Anaesthesiology, Raichur Institute of Medical Sciences, Raichur, Karnataka. Email: drvishalakshi_patil@yahoo.co.in, Mobile Number: 099008399299
Direct laryngoscopy and endotracheal intubation following induction of anaesthesia is associated with hemodynamic changes, due to reflex sympathetic discharge caused by epipharyngeal and laryngopharyngeal stimulation. This increased sympatho-adrenal activity may result in hypertension, tachycardia and arrhythmias. This increase in blood pressure and heart rate are usually transient, variable and unpredictable.
To study the cardiovascular changes following direct laryngoscopy and endotracheal intubation using the standard anaesthesia technique of induction with Thiopentone sodium and muscle relaxation with succinylcholine.
To compare the efficiency of 2% and 4% lignocaine nebulisation in attenuating the cardivascular response to direct laryngoscopy and intubation.
The patients are selected from Pre Anesthetic Clinic of Kidwai Memorial Institute of Oncology, Bangalore.
Prospective, randomised, double blinded and placebo controlled clinical study.
Inpatients of Kidwai Memorial Institute of Oncology aged between 17 yrs to 65 yrs scheduled for elective surgery under GA with ASA I and ASA II after approval from ethics committee and Consent from patients.
A Comparative controlled randomized clinical anesthesia study with three groups, with 90 patients randomized in to three groups, 30 patients in Group I (Control), 30 patients in Group II (2% Lignocaine Nebulasiation), 30 patients in Group III (4% Lignocaine Nebulisation) is undertaken to study cardiovascular changes(HR-heart rate, SBP-systolic blood pressure, DBP -diastolic blood pressure, MAP(mean arterial pressure) following direct larynoscopy and endotracheal intubation using standard anaesthesia technique, to compare efficiency of 2% and 4% lignocaine nebulisation.
Laryngoscopy and intubation caused a significant increase in heart rate and blood pressure. 4% lignocaine nebulisation was found to be more effect than 2% lignocaine nebulisation to attenuate the pressor response to laryngoscopy and intubation.
Lignocaine, Laryngoscopy, Intubation
