Indian Journal of Public Health Research & Development
  • Year: 2016
  • Volume: 7
  • Issue: 1

Study of Certain Biochemical Parameters in Bone Diseases with Special Reference to Sickle Cell Anemia

  • Author:
  • Tembhurnikar Rajesh1, Tembhurnikar Pankaj2, Nigam Prashant3,, Bagde Sadhana4
  • Total Page Count: 4
  • Page Number: 193 to 196

1 Associate Professor, Dept. of Orthopedics, GMC, Rajnandgon, Chhattisgarh

2Associate Professor, Dept. of Medicine, Chhattisgarh Institute of Medical Sciences, Bilaspur, Chhattisgarh

3Assistant Professor, Dept. of Biochemistry, Chhattisgarh Institute of Medical Sciences, Bilaspur, Chhattisgarh

4Associate Professor, Dept. of Pathology, Chhattisgarh Institute of Medical Sciences, Bilaspur, Chhattisgarh

*Corresponding author: Dr. Prashant Nigam, Assistant Professor, Dept. of Biochemistry Chhattisgarh Institute of Medical Sciences, Sadar Bazaar, Bilaspur, CG, 495001 Mob No. 09993604518. Email: nigam.prashant86@gmail.com

Online published on 16 January, 2016.

Abstract

The vasoocclusive process of sickle cell disease causes bone infractions, Osteomyelitis, Arthritis and many more complications. Inflammatory markers and other biochemical parameters could be explain the actual reason and proved helpful to overcome these complications.

In this study we performed CRP, IL-6, TNF-α, Homocysteine along with other routine biochemical parameters in 30 Sickle cell patients presented with various bone complications and compared them with 30 age matched normal subjects.

We found increased level of all inflammatory markers when compared to control group along with disturbed biochemical profile.

We concluded that high level of Inflammatory markers also predicts status of bone complications and helpful to assess the condition of patients.

Keywords

Bone Disease, Sickle Cell, Inflammatory Markers