1Associate Professor, Dept. of OBG, Kamineni Institute of Medical Sciences, Sreepuram, Narketpally
2Professor, Dept. of OBG, Kamineni Institute of Medical Sciences, Sreepuram, Narketpally
3Professor & HOD, Dept. of OBG, Kamineni Institute of Medical Sciences, Sreepuram, Narketpally
*Corresponding author: Dr Sunita Mishra, MD(OBG), Associate Professor, Dept.of OBG, Kamineni Institute of Medical Sciences, Sreepuram, Narketpally-508254. Nalgonda (dist), Telangana, E-mail ID: drmishrasunita@gmail.com, Mobile no.: 9573660173
Online published on 16 January, 2016.
To compare and evaluate the efficacy of drotaverine hydrochloride and valethamate bromide for effective cervical dilatation in labor.
Total of 100 patients (aged 20 to 30 years) including both primigravidae and multigravidae in first stage of labor, were divided randomly into two groups with 50 patients in each. The drotaverine (D) and valethamate (V) groups were given intravenously, 40 mg Drotaverine hydrochloride to the former with every 2 hours for a maximum of 3 doses and 8 mg Valethamate bromide to the latter with maximum of 6 doses half an hour apart.
In primigravidae and multigravidae the average duration of active phase is shortened by 3 hours with 1.92 cm/hour cervical dilatation in drotaverine group and 1 hour 45 minutes with 1.44 cm/hour in valethamate group (p value <0.05). There was no significant difference in the duration of second and third stages in both groups. No obstetrical complications or major side effects observed in both groups.
Drotaverine accelerates labor better than of valethamate. The reduction of pain during labor is better with drotaverine when compared with valethamate.
Cervical dilatation, drotaverine, valethamate
