1Ph.D. Scholar, Department of Biochemistry, Santosh Medical College, Ghaziabad, U.P.
2Assistant Professor, Department of Physiology, Venkateshwara Institute of Medical Sciences, Gajraula, U.P.
3Assistant Professor, Department of Microbiology, Venkateshwara Institute of Medical Sciences, Gajraula, U.P.
*Corresponding author: Gaurav Gupta, Ph.D. Scholar, Department of Biochemistry, Santosh Medical College & Hospital, Ghaziabad, U.P. Email: gaurav.ac.in@gmail.com, Mob-917417327421
Online published on 26 April, 2016.
Subclinical hypothyroidism characterised by elevated level of total cholesterol, is controversial. Females are more affected by subclinical hypothyroidism comparing to males.
Total 131 both male & female were enrolled for the study compared with 61 healthy controls. Body mass index, serum concentration of TSH and FT4 and Total cholesterol was measured. Thyroid profile of the participants was estimated by ELISA. Total cholesterol (TC) was measured by CHOD-POD method.
SCH patients were characterised by higher body mass index and elevated level of total cholesterol compared to control group (<0.01). Females with SCH were having higher BMI (<0.01) and higher total cholesterol (<0.05) when compared with male of SCH. TSH was positively correlated with TC in male group of SCH (r=0.32, p= <0.05) as well as female group of SCH(r=0.34, p=<0.05).
Hypercholesterolemia was associated with subclinical hypothyroidism. Females with SCH were characterised by higher risk of hypercholesterolemia comparing to males.
SCH, hypercholesterolemia, Thyroid stimulating hormone, BMI
