1Assistant Professor, Department of Pharmacology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India
2Associate Professor, Department of Pharmacology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India
3Assistant Professor, Department of Biochemistry, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India
Online published on 4 July, 2016.
Vitamin D deficiency is a worldwide health problem, the aims of the study was to see the level of Vitamin D in hypothyroidism. its role as an immune modulator on endocrinal system has been recently emphasized. The evidence is increasingly pointing towards vitamin D significant role in reducing the incidence of autoimmune diseases.
Thyroid hormones (TSH, T3 and T4) and Serum vitamin D (25-OH) levels were measured in 40 patients with hypothyroidism and 40 healthy subjects, utilizing the ELISA and spectophotometric method.
The serum level of total T3, total T4, TSH and Serum 25(OH) vitamin D was significantly lower in hypothyroid patients as compared to controls (p<0.001). Its level was lower in females than male patients.
Our results indicated that patients with hypothyroidism suffered from hypovitaminosis D that is significantly associated with the degree and severity of the hypothyroidism. It is advised vitamin D supplementation should be given to all hypothyroid patients.
Hypothyroidism, Thyroid diseases, Vitamin D deficiency
