Indian Journal of Public Health Research & Development
  • Year: 2016
  • Volume: 7
  • Issue: 4

Transaminitis in Dengue Fever: An Observational Study

1Assistant Professor, Department of Medicine, School of Medical Sciences and Research, Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh

2Associate Professor, Department of Medicine, School of Medical Sciences and Research, Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh

3Professor, Department of Medicine, School of Medical Sciences and Research, Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh

Online published on 14 October, 2016.

Abstract

Dengue fever is the most important vector borne disease worldwide. Though dengue virus is not a hepatotropic virus, isolated raised serum aminotransferases levels or transaminitis is a common feature of liver dysfunction in dengue fever.

Data of 114 IgM antibody confirmed cases of dengue fever was analysed with special attention to serum aminotransferase levels.

During 2013 outbreak dengue fever primarily affected younger age people. Apart from the typical manifestations of fever, headache, bodyache, pain abdomen, and vomiting; high levels of serum aminotransferases were present in most of the cases along with normal serum bilirubin levels.

All patients of dengue fever should be evaluated for liver functions as transaminitis is common finding in dengue. Further larger studies are needed to assess the possible correlation of aminotransferase enzymes levels with the duration of illness and outcome of the disease.

Keywords

Dengue fever, thrombocytopenia, aminotransferases, transaminitis