Indian Journal of Public Health Research & Development
  • Year: 2016
  • Volume: 7
  • Issue: 4

Retrospective Study of Central Nervous System Tumors in a Tertiary Health Care Centre

1Associate Professor, Department of Pathology, Mahatma Gandhi Medical College

2Professor & HOD, Department of Neurosurgery, Mahatma Gandhi Medical College

3Assistant Professor, Department of Neurosurgery, Mahatma Gandhi Medical College

*Corresponding author: Dr. Surabhi Tyagi Associate Professor Pathology, Mahatma Gandhi Medical College, Jaipur, Rajasthan Email = dr_tyagi_surabhi@yahoo.co.in

Online published on 14 October, 2016.

Abstract

Scenario in today's world shows definite rise in the incidence of CNS tumors. The CNS tumors are underdiagnosed & under-reported due to differences in pathological diagnosis & reporting. The WHO tumor classification is still not in universal use. Differences in diagnostic practices make the geographic especially international comparisons difficult. Reporting the cases is important for the statistics & epidemiological studies. There is no similar study to the best of my knowledge from the region of Rajasthan.

This paper is to elicit the spectrum of CNS tumors reported in our medical college in a period of last one year from January 2015 to December 2015.

This study was carried out at a tertiary health care centre from January 2015 to December 2015. All patients operated in the department of neurosurgery for space occupying lesions in CNS were enrolled. All radiological and relevant lab investigations were done. Final diagnosis was based on histopathological examination and immunohistochemistry whenever needed. Data on the CNS tumors was collected and analysed in terms of age, gender and current WHO classification of histopathological types.

Total of 139 CNS tumors were investigated and studied in last one year which revealed highest incidence of tumors of the sellar region-granular cell tumor of neurohypophysis and craniophyrangioma collectively comprising 45 cases (32.37%) of which pituitary adenoma alone stands out with a percentage of 28.77%. This was followed by astrocytomas (19.42%), with GBM having highest incidence (9.35%)

In contrast to other studies, which show highest incidence of GBM, this is the only study showing highest incidence of tumors of the sellar region-granular cell tumor of neurohypophysis and craniophyrangioma which is due to the facility of endoscopic surgery in our referral tertiary health care centre. Our centre is one of the very few centres in Rajasthan where Endoscopic endonasal surgery is done.

Keywords

CNS tumors, trends, incidence, developing countries