Comparative Evaluation of Delmopinol with Chlorhexidine Mouthrinse as an Anti-plaque Agent-a Clinical Study

This study evaluated the comparative efficacy of Delmopinol over Chlorhexidine as an anti-plaque agent and also determined that chemical plaque control has an additive effect over mechanical plaque control when used alone.

A randomized comparative, prospective, interventional, comparative, cross-over design was conducted (with institution and university approval for dissertation) to evaluate the efficacy of Delmopinol over Chlorhexidine as an anti-plaque agent and also to evaluate that chemical plaque control has additive effect over mechanical plaque control on two variables.

30 consecutive consenting patients were randomly selected irrespective of sex and an age range of 20–30 years, with overt gingivitis having gingival score (≥2). Clinical parameters like Plaque index, Gingival index, Probing depth and stain index were assessed. All the data were checked for normality at baseline and were found to be following a normal distribution (Kolmogorov-Smirnov test).

Analysis of data demonstrated that there were statistically significant reduction in plaque index, gingival index, probing depth and stain index in both the groups but plaque index was more reduced in Group I than Group II and equal reduction in Gingival index in both the groups.

The study indicates that the adjunctive use of chemical plaque control agents over mechanical oral hygiene resulted in more reduction in clinical parameters than mechanical oral hygiene measures alone. However, both are equally effective in reducing gingivitis.