Indian Journal of Public Health Research & Development
  • Year: 2017
  • Volume: 8
  • Issue: 2

A Study of Non Alcoholic Fatty Liver Disease (NAFLD) Diagnosed on Ultrasound with Association of Lipid Profile in Western Uttar Pradesh

  • Author:
  • Pankaj Kumar1,, Yatish2, Hemant Kumar Singh3, Ankita Sharma4, Vikash Kumar5, Vinay Sindhu6, Amit Saxena7
  • Total Page Count: 6
  • Page Number: 53 to 58

1Assistant Professor, Department of General Medicine, Saraswathi Institute of Medical Sciences, Hapur, U.P.

2Post Graduate III year, Department of General Medicine, Saraswathi Institute of Medical Sciences, Hapur, U.P.

3Associate Professor, Department of Community Medicine, Saraswathi Institute of Medical Sciences, Hapur, U.P.

4Post Graduate IIIrd year, Department of General Medicine, Saraswathi Institute of Medical Sciences, Hapur, U.P.

5Post Graduate III year, Department of Radiology, Saraswathi Institute of Medical Sciences, Hapur, U.P.

6Post Graduate III year, Department of General Medicine, Saraswathi Institute of Medical Sciences, Hapur, U.P.

7Post Graduate III year, Department of Pathology, Saraswathi Institute of Medical Sciences, Hapur, U.P.

*Corresponding author: Pankaj Kumar Assistant Professor, Department of General Medicine, Saraswathi Institute of Medical Sciences, Hapur, (U.P) E-mail: pankaj19822000@gmail.com Mob.: 9450136739

Online published on 11 April, 2017.

Abstract

To detect & compare lipid profile abnormalities in patients diagnosed with different grades of non-alcoholic fatty liver disease (NAFLD) on USG.

A Total of 200 ultrasound proven Non alcoholic fatty liver disease (NAFLD) patients were included in this study & investigated with serum lipid profile. A Comparison of lipid abnormalities between different grades of fatty liver which were diagnosed on USG was done. P value was calculated by using analysis of variance test (ANOVA) & P value <0.05 was considered as statistically significant.

Out of 200 cases which were diagnosed as NAFLD on USG, 39% were grade III followed by grade0-27%, gradeII-20%, gradeI-14%. On Statistical analysis we found increased values of total cholesterol, triglyceride, LDL, VLDL. The Total cholesterol level was significant, p<0.001 was higher among fatty liver grade III followed by grade o, gradeI, grade II & difference was significant. Similar observations were found for HDL, LDL & VLDL. Most of the patients had history of cholecystectomy which was more in females as compared to males.

We found abnormal lipid profile levels amongst patients with NAFLD. Though Liver biopsy is the gold standard method for diagnosis of NAFLD but a Case control study is recommended to find better understanding of lipid levels among NAFLD Subjects.

Keywords

Lipid level, Non-alcoholic fatty liver disease (NAFLD), Non alcoholic steato-hepatitis (NASH), Ultrasonography