1Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
*Correspondence author: Zulkifli Amin Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, Indonesia, 10430. Email: zulkifliamin52@gmail.com Phone: +62816819034
Online published on 11 April, 2017.
Air pollution is a serious and complex environmental health problem cause approximately 800000 premature deaths per year. Air pollution could leads to atherosclerosis progression through many biological and chemical pathways. Subsequent immune response and oxidative stress due to inhaled air pollution suggest hallmark mechanisms of air pollution in atherosclerosis formation. Other risk factors of atherosclerosis such as hypertension, dyslipidemia, and hyperhomocysteinemia also positively correlated with air pollution. Current animal and exposure studies have revealed correlation between air pollution, atherosclerosis, and its risk factors. Nevertheless, further investigation regarding this topic need to be intensified.
Air pollution, atherosclerosis
