1Laboratoire d'Anatomo-histo-pathologie, Institut Pasteur du Maroc
2Laboratoire d'Anatomo-cyto-pathologie, CHU-Ibn Rochd, Casablanca-Maroc
3Laboratoire de Neurosciences Pathologies intégrées et Substances naturelles, Faculté des Sciences et Techniques, Mohammedia-Maroc
4Laboratoire de Biologie et Santé, URAC 34, Faculté des sciences Ben'Msik-Casablanca
5Laboratoire de Génétique médicale, Faculté de Médecine et de Pharmacie
6Laboratoire de physiopathologie et Génétique moléculaire, Faculté des Sciences Ben'Msik-Casablanca
*Correspondance address: Hanaa AMRANI H J, Laboratoire d'Anatomie-pathologie, Institut Pasteur du Maroc, 1 Rue Louis Pasteur, 20100, Casablanca, Morocco Tel: +212 522 43 44 69/+212 670 99 99 52 Fax: +212 522 43 44 77/+212 522 26 09 57 E-Mail: hana.gradzie1@gmail.com
Online published on 11 April, 2017.
Rates of Helicobacter pylori infection appear to be higher in developing countries than in developed countries where they seem to be decreasing with improvements in hygiene practices. Few data are currently available on the prevalence of H. pylori infection in the Moroccan population.
We identified the medical records of 5172 symptomatic patients in order to determine the prevalence of H. pylori, and its association with the clinicopathological features and digestive disorders.
This is a retrospective comparative and descriptive study. The data were collected from screening archives of patients, suffering from recurrent abdominal pain or other similar symptoms, recruited between 1 January 2003 to 31 December 2008 in CHU Averroes-Casablanca and Pasteur Institute-Morocco. The data were processed and analyzed by Epi-Info software.
In total, 4032 (82.45%) were H. pylori-positive. H. pylori infection was closely correlated to age but not gender. Chronic gastritis associated with H. pylori diagnosis was the most common (94%) and associated severe glandular atrophy and intestinal metaplasia were observed, respectively, in 6.5% and 13% of cases. As for the topography, the antral mucosa was most frequently colonized (64.5%).
The Helicobacter infection may be considered as a significant risk factor for chronic gastritis, and the exact prevalence of H. pylori infection in gastric cancer patients in our studied population remains difficult to estimate, because infection can be lost from individuals with cancer. The very high frequency found in our population and generally in developing countries should incite us to make a systematic eradication, and to evaluate the interest of an annual screening of helicobacter pylori infection in our area.
Helicobacter pylori, chronic gastritis, ulcer, gastric cancer, epidemiology
