Indian Journal of Public Health Research & Development
  • Year: 2017
  • Volume: 8
  • Issue: 3

Preventive Role of Probiotic in Antibiotic Associated Diarrhoea in Children

1Associate Professor, Department of Pharmacology, MMC, Muzaffarnagar

2Professor, Department of Paediatric, MMC, Muzaffarnagar

3Professor, Department of Pharmacology, MMC, Muzaffarnagar

*Corresponding author: Dr Meenakshi Jindal Associate Professor, Department of Pharmacology, Muzaffarnagar Medical College, Muzaffarnagar, Email: drmeenakshijindal@rediffmail.com

Online published on 18 July, 2017.

Abstract

The study was carried out to assess the preventive role of Probiotic in antibiotic associated diarrhoea in children.

A randomized, open, parallel study was conducted in tertiary care hospital. 600 children in the age group of 6 months-12yrs, receiving beta lactam antibiotics for various ailments like Otitis media, Tonsillitis, UTI etc. were included in the study. All these children did not have diarrhoea. 300 out of 600 children were also given probiotic sachets along with beta lactam antibiotic.

72 [24%] out of 300 patients in Control group developed diarrhoea whereas only 16 [5.3%] out of 300 in the Test group developed diarrhoea. The results were stastistically significant [p < 0.001] as calculated by Chisquare test.

Probiotic was effective in preventing antibiotic induced diarrhoea in children in the Indian population. Hence, it can be used prophylactically to prevent AAD in children.

Keywords

Antibiotic associated diarrhoea [AAD], Probiotic