Indian Journal of Public Health Research & Development
  • Year: 2018
  • Volume: 9
  • Issue: 1

Bacterial and Viral Pathogen spectra of ARI among the Children Below 5 Years Age Group in tribal and Coastal Regions of odisha

  • Author:
  • Bhagyalaxmi Biswal1, Bhagirathi Dwibedi2, Jagadish Hansa3,5, Shantanu Kumar Kar4,
  • Total Page Count: 7
  • Page Number: 366 to 372

1PhD Scholar, ICMR-RMRC, Bhubaneswar, India

2Scientist-E, ICMR-RMRC, Bhubaneswar, India

3Scientist-B, Presently at ICMR-RMRIMS, Patna, India

4Director (Research), Directorate of Medical Research, IMS & SUM Hospital, Siksha O Anusandhan University

5Directorate of Medical Research, IMS & SUM Hospital, Siksha O Anusandhan University, Bhubaneswar, India

*Corresponding author: Dr Shantanu Kumar Kar Director (Research) medical & life Sciences Directorate of Medical Research, IMS & SUM Hospital, S ‘O ’A University, BBSR Former-Director RMRC, Bhubaneswar Email id-jagadish.hansa@gmail.com; +919437041322

Online published on 7 February, 2018.

Abstract

The study evaluates the spectra of viruses, bacteria and mix infection of both pathogens and its drug sensitivity pattern in hospitalized children presenting with Acute Respiratory Infections (ARI) in two geographical settings of Odisha, India.

Nasopharyngeal/Oropharyngial swabs cultured from 1063 ARIs affected children fallowing standard bacteriological culture method & antimicrobial susceptibility using CLSI guidelines and respiratory viruses by multiple reverse transcriptase polymerase chain reaction (RT-PCR).

Out of 1063 specimens 82.2% exhibited seasonal variation and presence of S. Pneumonia (31%), K. pneumaniae (32%), S. aureus, Streptococcus spp, M. pneumoniae, P. aeruginosa and Moraxilla spp bacterial pathogens. The viruses detected were RSV (12.1%), followed by HPIV-1 (5.6%), Influenza A (4.6%), and HMPV (2.8%). Co-existence of two or more pathogens was found in 116 (10.9%) specimens. Pathogen detection in less than 1-year was significantly higher (P =0.0039). The pathogens isolated in tribal region was significantly higher (52.2%, P<0.0015). Antimicrobial susceptibility indicates the presence of multidrug resistance, extended spectrum betalactamases (ESBL) (75%) and third generation cephalosporin's (87.4%), MRSA (16.6%) and Penicillin resistant S. pneumonia (84.7%).

The results indicate the need for use of appropriate drug regimens to address ARI in different geographical settings of the state.

Keywords

Infection, Pathogen, ARI