Analysis of serum uric acid in patients with chronic renal impairment a research

Two third of uric acid is excreted by kidneys. Therefore, it is expected for hyperuricaemia prevalence to increase in association with chronic renal impairment. Surveys had shown that hyperuricaemia is common in patients with chronic renal impairment. The present study aims to To assess the prevalence of elevation in serum uric acid in patients with chronic renal impairment and their association with age, sex, hypertension, level of serum creatinine and duration of chronic renal impairment. Results show that The prevalence of hyperuricaemia is 75%, 76% of males and 74% of females and in about 50% of them serum uric acid is below 9 mg/dl. 84% of hyperuricaemic patients with chronic renal impairment among males are hypertensive, while 75% of hyperuricaemic patients in female are hypertensive. Statistical analysis showed significant association of hyperuricaemia with age and level of serum creatinine, but no sex difference. Can be concluded that the Hyperuricaemia is a common finding in patients with chronic renal impairment of both sexes, and it is well associated with age, level of serum creatinine and hypertension.