Indian Journal of Public Health Research & Development
  • Year: 2018
  • Volume: 9
  • Issue: 11

Chemical synthesis and characterization of silver nanoparticles induced biocompatibility for anticancer activity

  • Author:
  • Ali Ibrahim Shkhair1, Mohammed Kareem Jabber2, Murtadha M-Hussein A-kadhim3, Abdullah Hasan Jabbar4
  • Total Page Count: 6
  • Page Number: 352 to 357

1Department of Dairy Technology, College of Food Science, AL-Qasim Green University, Ministry of Higher Education and Scientific Research, Iraq

2Faculty of Pharmacy, Alkafeel University College, Kufa, Iraq

3Department of Biotechnology, College of Biotechnology, AL-Qasim Green University, Ministry of Higher Education and Scientific Research, Iraq

4Department of Physics and Chemistry, Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia (UTHM), 84600, Pagoh

Online published on 7 December, 2018.

Abstract

Silver nanoparticles (AgNPs) have gained giant pastime of nanoscience due to the fact of its wide thoroughness over biomedical applications. Current research labor has been discontinued in imitation of look at anticancer endeavor concerning visible SNPs in opposition to ethnic most cancers cell lines. The photosynthesis of SNPs was done the usage of cloud extracts out of Salacia Chinensis (SC) as much a green supply in imitation of limit silver nitrate in imitation of nanoparticles. Nanoparticles are instituted above about quite a number techniques, particularly UV spectroscopy, infrared spectroscopy because of Fourier transform, X-ray diffraction, and scanning electron microscopy. The ultraviolet-visible spectrum regarding the made nanoparticles indicates the maximum peak at 420 nm. The results regarding infrared spectroscopy from Fourier exhibit the arrival regarding alcohols, fragrant compounds, or amines as point out the appearance or stabilization on proteins together with nanoparticles. The analysis on the energetic electron microscope suggests as the spherical silver nanoparticles are spherical along sizes ranging beside 11 according to 27 nm depending over the pH conditions. The effects on X-ray alteration analysis exhibit the emergence concerning silver nanoparticles then theirs lucid nature. The outcomes on it lesson furnish experimental evidence so SC-mixed SNPs be able object as like an anticancer agent and are promising to overcome the boundaries concerning traditional cancer chemotherapy.

Keywords

Silver nanoparticles, Chemical synthesis, anticancer activity, biocompatibility, Nanotechnology