1Department of Life Science and Biochemical Engineering, Graduate School, SunMoon University, Korea
2Genome-based BioIT Convergence Institute, Korea
3Department of Dental Hygiene, Gangneung Yeongdong University, Korea
4Department of Dental Hygiene, Sun Moon University, Korea
5Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University, Korea
*Corresponding Author: Tae-Jin Oh Professor, Department of Pharmaceutical Engineering and Biotechnology, SunMoon University, Korea Email: tjoh3782@sunmoon.ac.kr
Online published on 7 December, 2018.
The present study was conducted to investigate the antimicrobial potential of acetone, ethanol and ethyl EA of A. auricula-judaeagainst the growth of nine oral bacteria that cause dental caries and periodontal diseases.
The extracts of A. auricula-judae showed the antimicrobial activity against the tested oral bacteria. EA extract showed more antimicrobial activity than acetone and ethanol extracts. The highest antimicrobial activity of ethyl acetate extract from A.auricula-judae was obtained against A. viscosus, which resulted in an inhibition zone of 11.68 to 14.40 mm. This extract exhibited MIC values ranging from 0.23 to 3.75 mg/ml.
The present study aimed to verify the roles of A. auricula-judae as a natural product with antimicrobial potential for oral diseases by investigating the antimicrobial activities of various solvent extracts of A. auricula-judaeagainst oral bacteria causing dental caries and periodontal diseases. The ethyl acetate extracts from A. auricula-judae showed the antimicrobial activity against nine oral bacteria better than different solvent. The present study aimed to verify the roles of A. auricular-judaeas natural product with antimicrobial potential for oral diseases by investigating the antimicrobial activities of various solvent extracts of A. auricular-judae against oral bacteria causing dental caries and periodontal diseases.
This Auricularia auricula-judae may be considered as an effective natural source of antimicrobial agent for the prevention of oral pathogens.
Antimicrobial activity, growth inhibition, Auricularia auricula-judae, minimum inhibitory concentration, oral pathogen
